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Retatrutide dosage calculator

Retatrutide's six-day half-life supports weekly dosing with steady accumulation. Because trial protocols escalate slowly over many weeks, reconstitute for the dose you are on now, not your target.

Half-life ~6 days2mg weekly, escalated over 12+ weeks
AI-built tool. Cross-check critical values against authoritative sources before use.

Retatrutide dose

Seeded with a common Retatrutide protocol. Adjust to match yours.

Draw to

80.0 IU

0.800 mL · 5.00 mg/mL · 2 doses / vial

010203040506070809010080.0INSULIN · U-100IU

Steady state (4mg every 7d)

Time to steady

30 days

Accumulation

1.80x

Mean (Css)

4.94 mg

How to reconstitute Retatrutide

STEP 1

Add bacteriostatic water

Trickle 2mL of BAC water down the inside wall of the 10mg vial. That gives a 5.00 mg/mL solution.

STEP 2

Swirl, do not shake

Rotate gently until fully dissolved. Shaking shears the peptide.

STEP 3

Draw your 4000mcg dose

Pull to 80.0 IU (0.800 mL). One 10mg vial yields about 2 doses.

STEP 4

Refrigerate between uses

Store the reconstituted vial at 2-8°C and use within a few weeks.

Retatrutide dosing questions

How do I reconstitute Retatrutide?+

Add 2mL of bacteriostatic water to a 10mg Retatrutide vial. That produces a 5.00 mg/mL (5000 mcg/mL) solution. For a 4000mcg dose you then draw 0.800 mL.

How many units of Retatrutide do I draw for a 4000mcg dose?+

On a U-100 insulin syringe, draw to 80.0 units (0.800 mL). Adjust the inputs above if your vial or water volume differs.

How many Retatrutide doses are in one vial?+

A 10mg vial dosed at 4000mcg gives about 2 doses.

What is Retatrutide's half-life?+

Retatrutide has a half-life of ~6 days. A typical protocol is 2mg weekly, escalated over 12+ weeks. Retatrutide's six-day half-life supports weekly dosing with steady accumulation. Because trial protocols escalate slowly over many weeks, reconstitute for the dose you are on now, not your target.

How long until Retatrutide reaches steady state?+

With a ~6 days half-life, Retatrutide reaches steady state after roughly five half-lives. The steady-state read-out above shows the accumulation factor and mean level for the seeded weekly dose.

Next Step

Turn the Retatrutide math into a protocol

You have the reconstitution and dosing numbers for Retatrutide. The useful follow-up is the full guide and then sourcing the compound deliberately.

Guide

Read the Retatrutide guide

Mechanism, dosing context, storage, and the supporting literature behind the numbers.

Open Retatrutide guide

Dosing

Retatrutide dosage chart

Protocol-by-protocol dosing schedules for different research goals.

View dosage chart

Source

Source Retatrutide

Once the math checks out, move to the compound page and keep ENHANCED ready.

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