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Growth Factor / MuscleInjectableResearch Protocol

IGF-1 LR3 (Long R3) Dosage Chart

IGF-1 LR3 is a modified IGF-1 analog with an N-terminal extension and an Arg3 substitution that weaken IGF-binding-protein binding and extend circulation, studied for cell proliferation and muscle. Note two things up front: the 'Long' refers to the peptide extension, not the half-life, and the widely quoted 20-30 hour half-life is vendor lore rather than a clean human PK figure. Hypoglycemia is a real risk.

AI-built tool. Cross-check critical values against authoritative sources before use.

Half-life

Commonly cited ~20-30 hours (vendor figure, not a clean human PK value)

Format

Injectable

Purity

≥98%

Protocols

2 variants

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Research Protocols

Dosage Protocols

Each row reflects a common research protocol variant. These are reference ranges derived from published literature and community research — not medical guidance.

Protocol 1

Standard Research Convention

4-week blocks, then off

Dose

20-50mcg per day subcutaneous

Duration

4-week blocks, then off

The dose most research protocols circulate. Because IGF-1 LR3 is insulin-adjacent, blood glucose can drop; dosing with food is common. Human performance data does not exist, so this is convention, not evidence.

Protocol 2

Localized (site-injection) theory

Post-workout, as studied

Dose

20-50mcg into or near a trained muscle

Duration

Post-workout, as studied

The bodybuilding theory of injecting near a worked muscle for local effect. There is no human study showing injection-site-specific hypertrophy; treat it as an unproven hypothesis.

Mixing Math

Reconstitution

Reference values for preparing a research vial. Adjust the syringe reading if you change the water volume.

Vial size

1mg vial

BAC water

2ml bacteriostatic water

Concentration

0.5mg/ml (500mcg/ml)

Dose / ml

50mcg = 0.1ml

Syringe units

10 IU per 50mcg on a U-100 syringe

Need help converting different vial sizes? Use our reconstitution calculator to generate protocol-specific numbers instantly.

Storage

Handling Notes

Lyophilized: -20°C long-term, 2-8°C short-term. Reconstituted: refrigerate at 2-8°C and use within about 21-28 days. Some researchers reconstitute with a dilute acetic-acid solution; bacteriostatic water is the common choice. Do not freeze the reconstituted solution.

Research Considerations

Cautions

  • HYPOGLYCEMIA: IGF-1 is an insulin cousin and can lower blood glucose sharply, even without insulin present. This is the primary acute risk; never dose fasted without understanding it.
  • IGF-1R activation is a proliferative, anti-apoptotic signal, so elevated IGF-1 tone is a theoretical concern for cancer risk.
  • Circulating half-life figures for IGF-1 LR3 are vendor claims, not established human pharmacokinetics.
  • No human performance or hypertrophy trials exist. IGF-1 LR3 is a research compound not approved for human use; source only COA-verified material.

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Research use only. Not medical advice. Browse all dosage charts