Peptide Calculator
Semaglutide dosage calculator
Semaglutide's seven-day half-life is what makes once-weekly dosing work: levels accumulate across the first month and plateau around week five. Reconstitute conservatively so the early titration doses stay easy to draw.
Semaglutide dose
Seeded with a common Semaglutide protocol. Adjust to match yours.
Draw to
10.0 IU
0.100 mL · 2.50 mg/mL · 20 doses / vial
Dose is small. A U-100 ½ mL syringe doubles your reading precision for microdoses.
Steady state (1mg every 7d)
Time to steady
35 days
Accumulation
2.00x
Mean (Css)
1.44 mg
How to reconstitute Semaglutide
STEP 1
Add bacteriostatic water
Trickle 2mL of BAC water down the inside wall of the 5mg vial. That gives a 2.50 mg/mL solution.
STEP 2
Swirl, do not shake
Rotate gently until fully dissolved. Shaking shears the peptide.
STEP 3
Draw your 250mcg dose
Pull to 10.0 IU (0.100 mL). One 5mg vial yields about 20 doses.
STEP 4
Refrigerate between uses
Store the reconstituted vial at 2-8°C and use within a few weeks.
Semaglutide dosing questions
How do I reconstitute Semaglutide?+
Add 2mL of bacteriostatic water to a 5mg Semaglutide vial. That produces a 2.50 mg/mL (2500 mcg/mL) solution. For a 250mcg dose you then draw 0.100 mL.
How many units of Semaglutide do I draw for a 250mcg dose?+
On a U-100 insulin syringe, draw to 10.0 units (0.100 mL). Adjust the inputs above if your vial or water volume differs.
How many Semaglutide doses are in one vial?+
A 5mg vial dosed at 250mcg gives about 20 doses.
What is Semaglutide's half-life?+
Semaglutide has a half-life of ~7 days. A typical protocol is 0.25mg weekly, titrated up every 4 weeks. Semaglutide's seven-day half-life is what makes once-weekly dosing work: levels accumulate across the first month and plateau around week five. Reconstitute conservatively so the early titration doses stay easy to draw.
How long until Semaglutide reaches steady state?+
With a ~7 days half-life, Semaglutide reaches steady state after roughly five half-lives. The steady-state read-out above shows the accumulation factor and mean level for the seeded weekly dose.
Next Step
Turn the Semaglutide math into a protocol
You have the reconstitution and dosing numbers for Semaglutide. The useful follow-up is the full guide and then sourcing the compound deliberately.
Guide
Read the Semaglutide guide
Mechanism, dosing context, storage, and the supporting literature behind the numbers.
Open Semaglutide guideDosing
Semaglutide dosage chart
Protocol-by-protocol dosing schedules for different research goals.
View dosage chartSource
Source Semaglutide
Once the math checks out, move to the compound page and keep ENHANCED ready.
Shop Semaglutide