FOXO4-DRI Dosage Chart
FOXO4-DRI (FOXO4-D-Retro-Inverso) is a research senolytic peptide studied for selective clearance of senescent cells via disruption of the FOXO4-p53 interaction.
Half-life
Short (minutes in plasma)
Format
Injectable
Purity
≥97%
Protocols
3 variants
Research Protocols
Dosage Protocols
Each row reflects a common research protocol variant. These are reference ranges derived from published literature and community research — not medical guidance.
Protocol 1
Pulse Research Protocol
Dose
5mg subcutaneous every other day
Duration
3 doses per cycle
Mirrors the pulsed dosing rationale from the original de Keizer lab research — high concentration, short exposure window.
Protocol 2
Extended Pulse Protocol
Dose
5mg every 48h
Duration
3-6 doses over 2 weeks
Extended version of the pulse model used in some community research logs. Always followed by a recovery window.
Protocol 3
Micro Pulse Protocol
Dose
2.5mg every 72h
Duration
4-6 doses
Reduced exposure variant sometimes used to evaluate tolerability before progressing to full pulse doses.
Mixing Math
Reconstitution
Reference values for preparing a research vial. Adjust the syringe reading if you change the water volume.
Vial size
10mg vial
BAC water
2ml bacteriostatic water
Concentration
5mg/ml
Dose / ml
5mg = 1.0ml
Syringe units
100 IU on U-100
Frequently Paired
Common Stacks
Storage
Handling Notes
Lyophilized: -20°C preferred long-term, 2-8°C short-term. Reconstituted: refrigerate at 2-8°C, use within 14 days. Protect from light.
Research Considerations
Cautions
- FOXO4-DRI is strictly a research compound — no approved human indications exist.
- Senolytic mechanisms can trigger transient inflammatory markers; monitor closely.
- Pulsed schedules are preferred over continuous dosing to align with research rationale.
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Buy FOXO4-DRI nowResearch use only. Not medical advice. Browse all dosage charts