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Growth HormoneOralResearch Protocol

MK-677 (Ibutamoren) Dosage Chart

MK-677 (Ibutamoren) is an orally-active ghrelin receptor agonist studied as a growth hormone secretagogue. Supports once-daily protocols due to its ~24h half-life.

AI-built tool. Cross-check critical values against authoritative sources before use.

Half-life

~24 hours

Format

Oral

Purity

≥99%

Protocols

4 variants

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Research Protocols

Dosage Protocols

Each row reflects a common research protocol variant. These are reference ranges derived from published literature and community research — not medical guidance.

Protocol 1

Entry Research Protocol

8-12 weeks

Dose

10mg once daily (evening)

Duration

8-12 weeks

Low-side-effect entry dose for initial research. Evening dosing aligns with the natural GH pulse window during sleep.

Protocol 2

Standard Research Protocol

12-16 weeks

Dose

20mg once daily (evening)

Duration

12-16 weeks

Most commonly referenced dose in peptide research literature. Monitor water retention and insulin sensitivity markers.

Protocol 3

Elevated Research Protocol

8-12 weeks

Dose

25mg once daily

Duration

8-12 weeks

Upper end of community research range. Not recommended as a first cycle; requires established tolerance.

Protocol 4

Split Dose Protocol

12-16 weeks

Dose

10mg AM + 10mg PM

Duration

12-16 weeks

Split dosing has been used to smooth plasma levels and reduce next-day lethargy reports.

Mixing Math

Reconstitution

Reference values for preparing a research vial. Adjust the syringe reading if you change the water volume.

Vial size

Oral capsules (10mg or 25mg)

BAC water

N/A — oral

Concentration

10mg or 25mg per capsule

Dose / ml

N/A

Syringe units

N/A

Need help converting different vial sizes? Use our reconstitution calculator to generate protocol-specific numbers instantly.

Storage

Handling Notes

Store at room temperature (20-25°C), in a sealed container away from moisture and direct sunlight. Liquid oral formulations should be refrigerated after opening.

Research Considerations

Cautions

  • Known to elevate fasting glucose and insulin markers — baseline bloodwork is essential.
  • Water retention and increased appetite are common research observations.
  • Not appropriate during cutting-phase research unless carefully controlled.

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Research use only. Not medical advice. Browse all dosage charts