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ImmuneNasalResearch Protocol

VIP (Vasoactive Intestinal Peptide) Dosage Chart

VIP is a 28-amino-acid neuropeptide with pleiotropic immune, vasoregulatory, and neuroendocrine functions (Delgado & Ganea, Amino Acids 2013). Because its systemic half-life is only a couple of minutes, research protocols almost always use intranasal delivery rather than injection.

AI-built tool. Cross-check critical values against authoritative sources before use.

Half-life

~1-2 minutes (systemic); intranasal delivery is standard

Format

Nasal

Purity

≥98%

Protocols

3 variants

Research Protocols

Dosage Protocols

Each row reflects a common research protocol variant. These are reference ranges derived from published literature and community research — not medical guidance.

Protocol 1

Standard Intranasal Research Protocol

4-12 weeks

Dose

50mcg per spray, 1 spray up to 4 times daily

Duration

4-12 weeks

Mirrors the intranasal VIP protocol used in chronic inflammatory research. Start low and titrate frequency upward as tolerated.

Protocol 2

Conservative Entry Protocol

1-2 weeks before increasing

Dose

50mcg once daily (single actuation)

Duration

1-2 weeks before increasing

VIP is a vasodilator; a single daily actuation lets researchers assess blood-pressure and flushing response before adding doses.

Protocol 3

Maintenance Protocol

Ongoing (cycled)

Dose

50mcg 1-2 times daily

Duration

Ongoing (cycled)

Reduced-frequency dosing after an initial titration window.

Mixing Math

Reconstitution

Reference values for preparing a research vial. Adjust the syringe reading if you change the water volume.

Vial size

10mg vial (intranasal spray preparation)

BAC water

Reconstitute per compounding protocol into a nasal sprayer

Concentration

~50mcg per 0.1ml actuation

Dose / ml

50mcg = one spray actuation

Syringe units

N/A — intranasal, not injected

Need help converting different vial sizes? Use our reconstitution calculator to generate protocol-specific numbers instantly.

Frequently Paired

Common Stacks

Storage

Handling Notes

VIP is fragile. Keep the lyophilized vial frozen (-20°C) until use; refrigerate the reconstituted nasal solution at 2-8°C and use within the compounder's stated window. Protect from light and heat.

Research Considerations

Cautions

  • VIP is a potent vasodilator and can lower blood pressure and cause flushing; assess response before increasing frequency.
  • VIP is a research compound not approved for human use. Source only COA-verified material.
  • Most protocols derive from a specific chronic-inflammatory research context and are not validated for general use.

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Research use only. Not medical advice. Browse all dosage charts