CJC-1295 Dosage Chart
CJC-1295 is a synthetic GHRH analog sold in two distinct forms that dose completely differently. With DAC (drug affinity complex) it binds serum albumin for a 5.8-8.1 day half-life and sustained GH and IGF-1 elevation, characterized in humans by Teichman et al. 2006 (PMID 16352683). Without DAC (modified GRF 1-29) the half-life is roughly 30 minutes, so it is pulsed several times daily and usually paired with a ghrelin agonist such as Ipamorelin (Raun et al. 1998, PMID 9849822).
Half-life
With DAC ~6-8 days (5.8-8.1) · No DAC ~30 minutes
Format
Injectable
Purity
≥98%
Protocols
5 variants
Research Protocols
Dosage Protocols
Each row reflects a common research protocol variant. These are reference ranges derived from published literature and community research — not medical guidance.
Protocol 1
With DAC - Standard Protocol
Dose
1-2mg once weekly, subcutaneous
Duration
12-16 weeks
The long-acting form. In Teichman 2006 a single dose raised GH 2 to 10-fold for 6+ days and IGF-1 for 9-11 days, with IGF-1 staying above baseline up to 28 days across repeated weekly dosing. Produces a sustained elevation rather than discrete pulses.
Protocol 2
With DAC - Conservative Entry
Dose
1mg once weekly
Duration
12 weeks
Lower weekly dose to gauge IGF-1 response before titrating. The DAC form does not need empty-stomach timing because its action spans days, not a single pulse.
Protocol 3
No DAC (Mod GRF 1-29) - Standard Protocol
Dose
100mcg 1x daily, pre-bed, subcutaneous
Duration
12-16 weeks
The short-acting form. Give on an empty stomach (3+ hours fasted) so a carbohydrate or insulin spike does not blunt the GH pulse. Commonly co-administered with Ipamorelin 100mcg in the same syringe.
Protocol 4
No DAC - Multi-Pulse Protocol
Dose
100mcg 2-3x daily (AM, post-workout, pre-bed)
Duration
12-16 weeks
Multi-pulse pattern that suits the ~30 minute half-life of the no-DAC form. Each pulse needs its own empty-stomach window. Mirrors the pulsatile approach used with GHRH-1-29 analogs.
Protocol 5
Saturation Dose Reference
Dose
No DAC ~100mcg per pulse (saturating dose)
Duration
Per-pulse
Research on GHRH analogs suggests the GH response saturates near 100mcg per pulse for the no-DAC form. Useful as an upper-bound reference, not a target to exceed.
Mixing Math
Reconstitution
Reference values for preparing a research vial. Adjust the syringe reading if you change the water volume.
Vial size
2mg vial (either form)
BAC water
2ml BAC water
Concentration
1mg/ml (1000mcg/ml)
Dose / ml
No DAC 100mcg = 0.1ml · With DAC 1mg = 1ml
Syringe units
No DAC 100mcg = 10 IU · With DAC 1mg = 100 IU on U-100
Frequently Paired
Common Stacks
Storage
Handling Notes
Lyophilized: 2-8°C preferred, -20°C for long-term storage. Reconstituted: refrigerate at 2-8°C, protect from light. Use the no-DAC form within 14 days of reconstitution; the DAC form is stable for roughly 28-30 days.
Research Considerations
Cautions
- The DAC and no-DAC forms are NOT interchangeable. With DAC is dosed in milligrams once weekly; no DAC is dosed in micrograms several times daily. Confirm which form your vial is before calculating anything.
- The DAC form holds GH and IGF-1 elevated continuously, which removes the natural pulsatile pattern. Some researchers prefer the no-DAC form specifically to preserve pulsatility.
- Empty-stomach timing matters for the no-DAC form only. Carbohydrate or insulin within 60 minutes of a pulse blunts the GH release.
- Discontinue at least 48 hours before any GH or IGF-1 lab draw to avoid artificially elevated readings.
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