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Anti-InflammatoryInjectableResearch Protocol

KPV Dosage Chart

KPV is the C-terminal tripeptide (Lys-Pro-Val) of alpha-MSH, studied for anti-inflammatory activity through downregulation of NF-kB and pro-inflammatory cytokine signaling. It is orally active via PepT1 transport, which is why it appears both as an injectable vial and as oral capsules (Dalmasso et al., Gastroenterology 2008).

AI-built tool. Cross-check critical values against authoritative sources before use.

Half-life

Short (rapidly cleared systemically; acts intracellularly)

Format

Injectable

Purity

≥99%

Protocols

4 variants

Research Protocols

Dosage Protocols

Each row reflects a common research protocol variant. These are reference ranges derived from published literature and community research — not medical guidance.

Protocol 1

Standard Research Protocol (subcutaneous)

4-8 weeks

Dose

250-500mcg once daily

Duration

4-8 weeks

Most commonly cited research range for systemic anti-inflammatory exploration. Administered subcutaneously; rotate sites. Reassess after 4 weeks before extending.

Protocol 2

Oral / Gut-Focused Protocol

4-8 weeks

Dose

250mcg 1-2 times daily (oral capsule)

Duration

4-8 weeks

KPV's PepT1-mediated uptake makes the oral route viable for gut-localized research. Matches the common 250mcg capsule format. Taken with or without food.

Protocol 3

Elevated Research Protocol

3-6 weeks

Dose

500mcg-1mg daily

Duration

3-6 weeks

Upper end of the reported research range. Limit duration and revert to the standard protocol thereafter.

Protocol 4

Maintenance Protocol

Ongoing (cycled)

Dose

250mcg every other day

Duration

Ongoing (cycled)

Reduced-frequency dosing used to preserve effect while lowering cumulative exposure after an initial phase.

Mixing Math

Reconstitution

Reference values for preparing a research vial. Adjust the syringe reading if you change the water volume.

Vial size

10mg vial

BAC water

2ml bacteriostatic water

Concentration

5mg/ml (5000mcg/ml)

Dose / ml

250mcg = 0.05ml · 500mcg = 0.1ml

Syringe units

5 IU (250mcg) · 10 IU (500mcg) on a U-100 syringe

Need help converting different vial sizes? Use our reconstitution calculator to generate protocol-specific numbers instantly.

Storage

Handling Notes

Lyophilized: 2-8°C preferred, -20°C for extended storage. Reconstituted: refrigerate at 2-8°C and use within about 28 days. Protect from light. Oral capsules store at room temperature, sealed and dry.

Research Considerations

Cautions

  • KPV is a research compound not approved for human use. Source only COA-verified material.
  • Anti-inflammatory activity is derived largely from cell and animal models; human clinical data is limited.
  • Gut-focused protocols are exploratory; there is no established therapeutic dose.

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Research use only. Not medical advice. Browse all dosage charts