Thymosin Alpha-1
Immune-modulating peptide studied for immune support
Half-life
~2 hours
Typical Dose
1.6mg twice weekly
Format
Injectable
Purity
≥98%

Overview
Thymosin Alpha-1 is a peptide hormone naturally produced by the thymus gland. Studied for immune system modulation, infectious disease support, and adjuvant cancer research.
Sequence & properties
Sequence, colored by side chain
Length
28 aa
Avg mass
3,066.3 Da
Theoretical pI
3.99
Net charge (pH 7)
-5.0
Mechanism
Stimulates differentiation of T-cell precursors and modulates innate and adaptive immune responses through Toll-like receptor activation.
Researched benefits
- T-cell maturation support
- Immune system modulation
- Antiviral research
- Adjuvant in oncology research
Frequently asked
What does thymosin alpha-1 do?
It is a 28-amino-acid peptide derived from prothymosin alpha that modulates immune function, primarily by supporting T-cell maturation and signaling through Toll-like receptors. It is an immune modulator rather than a direct antimicrobial.
Is thymosin alpha-1 an approved drug?
Yes, in a number of countries. It is marketed as Zadaxin and approved in over 30 countries for hepatitis B and C and as a vaccine adjuvant, though it is not FDA-approved in the United States.
Is thymosin alpha-1 related to TB-500?
Only by name. Thymosin alpha-1 and Thymosin Beta-4 are structurally unrelated peptides with different functions. Alpha-1 is immunomodulatory; Beta-4 is involved in actin regulation and tissue repair.
How is thymosin alpha-1 dosed?
Clinical protocols use subcutaneous injection, typically twice weekly, with the schedule set by indication. Its immune-modulating action does not require daily administration.
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