KLOW Blend
GHK-Cu + BPC-157 + TB-500 + KPV — the premium 4-peptide skin & gut formulation
Price
$180
Compounds
4 peptides
Category
Skin & Anti-Aging
Format
Pre-Mixed Injectable
Overview
The KLOW Blend is the premium 4-peptide formulation from Ascension Peptides: GHK-Cu + BPC-157 + TB-500 + KPV. It builds on the GLOW Blend by adding KPV — a potent anti-inflammatory tripeptide derived from alpha-MSH (alpha-Melanocyte Stimulating Hormone) — creating the most comprehensive recovery, skin, and gut-health stack available in a single vial.
KPV (Lys-Pro-Val) is a C-terminal fragment of alpha-MSH that retains the parent molecule's powerful anti-inflammatory properties without its melanogenic (skin-darkening) effects. In research models, KPV has shown efficacy in intestinal inflammation (IBD models), skin inflammation, and systemic immune modulation via NF-κB pathway inhibition.
The four-compound combination covers local tissue repair (BPC-157), systemic healing (TB-500), matrix remodeling and skin rejuvenation (GHK-Cu), and targeted anti-inflammatory action (KPV) — a full-spectrum approach to recovery that addresses inflammation, healing, and regeneration simultaneously.
Why this combination works
Each of the four compounds addresses a distinct node in the recovery and repair network. BPC-157 drives local angiogenesis and growth factor upregulation at the tissue level. TB-500 supports systemic cell migration and anti-inflammation via actin regulation. GHK-Cu rebuilds the extracellular matrix — collagen, elastin, and decorin production. KPV directly inhibits NF-κB-mediated inflammatory signaling, providing a targeted immunomodulatory layer that complements TB-500's broader anti-inflammatory action. The result is four-layer coverage: local repair → systemic healing → matrix rebuilding → inflammatory resolution.
What's inside
GHK-Cu
~2-3 hours half-lifeCopper tripeptide driving collagen/elastin synthesis and extracellular matrix remodeling. The skin rejuvenation and structural repair layer.
BPC-157
~4 hours half-lifeLocal tissue repair via VEGF upregulation and angiogenesis. The targeted healing compound for tendon, ligament, and gut tissue.
TB-500
~2-3 hours half-lifeSystemic anti-inflammatory and cell-migration support. Provides the body-wide healing context through actin regulation.
KPV
~1 hour half-lifeAlpha-MSH-derived tripeptide that inhibits NF-κB inflammatory signaling. Researched for gut (IBD), skin inflammation, and immune modulation — without melanogenic effects.
Researched benefits
- Four complementary peptides covering all stages of recovery and repair
- KPV adds targeted NF-κB anti-inflammatory action not present in GLOW
- Researched for gut health (IBD models), skin inflammation, and systemic recovery
- Complete matrix remodeling via GHK-Cu collagen/elastin pathway
- BPC-157 + TB-500 foundation for proven musculoskeletal recovery
- Premium single-vial convenience — one reconstitution for a 4-compound protocol
Dosing & reconstitution
Research dosing
Research protocols typically use a daily subcutaneous injection drawn from the reconstituted vial. The pre-mixed ratio delivers proportional amounts of all four compounds per draw. Cycles run 4-8 weeks. As with all multi-peptide stacks, consult the vial label for the specific per-compound breakdown and adjust draw volume accordingly.
Reconstitution
Add 2 mL of bacteriostatic water to the vial for a working concentration. Inject water slowly along the vial wall, swirl gently. Do not shake. Refrigerate immediately and use within 21-28 days.
Open reconstitution calculatorFrequently asked
What does KLOW add over the GLOW Blend?
KLOW adds KPV — a targeted anti-inflammatory tripeptide that inhibits NF-κB signaling. While TB-500 in the GLOW Blend provides general anti-inflammatory support, KPV adds a specific immunomodulatory layer particularly relevant to gut inflammation (IBD models) and skin inflammatory conditions. Researchers studying gut-skin axis connections often prefer KLOW for this reason.
Is KPV the same as Melanotan / alpha-MSH?
KPV is a C-terminal tripeptide fragment (Lys-Pro-Val) derived from alpha-MSH. It retains the anti-inflammatory properties of the parent molecule but does NOT cause melanogenesis (skin darkening) — that effect resides in a different part of the alpha-MSH molecule. KPV is purely an anti-inflammatory agent.
Can I start with GLOW and upgrade to KLOW later?
Yes — GLOW and KLOW share the same GHK-Cu + BPC-157 + TB-500 foundation. Starting with GLOW is common for researchers who want to establish a baseline before adding the KPV anti-inflammatory layer. The compounds don't conflict, so transitioning between the two is straightforward.
Ready to start your research
Get the KLOW Blend from Ascension Peptides
4 compounds, one vial, one reconstitution. COA-verified, US-based, discreet shipping. Use code ENHANCED for 50% off your entire order.
Buy KLOW Blend — $180